What is the Biggest Casino in Vegas? The flower-filled combo of the Wynn and Encore resorts win the title of the biggest casino in Sin City. This luxury resort betting floor features 191,424-square-feet of space with over 1,800 slot machines and 180 table games to satisfy your gambling fantasy.

With a whopping 175 casinos throughout the metropolis, Las Vegas is the destination for table games, slot machines, and almost every other type of gambling you can imagine. Whether you're a first-timer or a seasoned gambler, knowing what to do in a casino is key.